ZocorŪ
(Simvastatin) Tablets

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Uses of Zocor

ZOCOR is a prescription drug that is indicated as an addition to diet for many patients with high cholesterol when diet and exercise are inadequate. For patients with coronary heart disease (CHD) and high cholesterol, ZOCOR is indicated as an addition to diet to reduce the risk of death by reducing coronary death; to reduce the risk of heart attack; to reduce the risk for undergoing cardiac procedures (coronary artery bypass grafting and percutaneous transluminal coronary angioplasty); and to reduce the risk of stroke or transient ischemic attack (TIA).

Simvastatin comes in tablets to take by mouth. It usually is taken once a day at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take simvastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take simvastatin even if you feel well. Do not stop taking simvastatin without talking to your doctor.

Before taking simvastatin,

• tell your doctor and pharmacist if you are allergic to simvastatin or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids, anticoagulants ('blood thinners') such as warfarin (Coumadin), cholestyramine (Questran), clarithromycin (Biaxin), clofibrate (Atromid-S), cyclosporine (Sandimmune, Neoral), digoxin (Lanoxin), erythromycin, fenofibrate (TriCor), gemfibrozil (Lopid), HIV protease inhibitors such as ritonavir (Norvir) and saquinavir (Invirase), itraconazole (Sporanox), ketoconazole (Nizoral), nefazodone (Serzone), niacin (nicotinic acid), and vitamins.
• tell your doctor if you have or have ever had liver, kidney, or heart disease; a severe infection; low blood pressure; or seizures.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking simvastatin, stop taking simvastatin and call your doctor immediately. Simvastatin can harm the fetus.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking simvastatin.
• talk to your doctor about the safe use of alcohol while taking this drug. Alcohol increases the side effects caused by simvastatin.
• plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Simvastatin may make your skin sensitive to sunlight.

  Avoid drinking large quantities of grapefruit juice (more than 1 quart a day) while taking simvastatin.

  Eat a low-cholesterol, low-fat diet. This kind of diet includes cottage cheese, fat-free milk, fish (not canned in oil), vegetables, poultry, egg whites, and polyunsaturated oils and margarines (corn, safflower, canola, and soybean oils). Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, lard, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips, coconut, cheese (other than cottage cheese), coconut oil, palm oil, and fried foods.